Isaac Guerendo

24-Year-Old Running BackRB
2024 Fantasy Outlook
A 4.33 40-yard time and a strong overall performance at the Combine launched Guerendo up draft boards, and the 49ers traded up in the fourth round to make sure they got the 221-pound speedster. Kyle Shanahan's offense is arguably the best in the league for a running back, especially one with game-breaking speed, though Guerendo figures to begin his career behind three-down workhorse Christian McCaffrey and the brittle Elijah Mitchell. Guerendo was never a lead back during his time at Wisconsin and Louisville, but he averaged 6.1 yards on 132 carries for the Cardinals last season and now becomes one of the fastest running backs in the NFL. Read Past Outlooks
RANKS
#456.17
ADP
$Signed a four-year, $4.72 million contract with the 49ers in May of 2024.
No touches on 13 snaps
RBSan Francisco 49ers
September 10, 2024
Guerendo (groin) suited up for Monday's season opener against the Jets but did not record a touch in a 32-19 win.
ANALYSIS
Guerendo made the 49ers' 53-man roster but was battling a groin injury heading into Week 1. The fourth-round pick out of Louisville got the green light and wound up logging 10 snaps on special teams and three on offense. Starter Christian McCaffrey (calf/Achilles) did not suit up for this contest, allowing Jordan Mason (28-147-1) to go off against the Jets. Guerendo appears to be next in line should San Francisco need a runner behind CMC or Mason this season.
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NFL Stats
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Fantasy/Red Zone Stats
See red zone opportunities inside the 20, 10 and 5-yard lines along with the percentage of time they converted the opportunity into a touchdown.
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2024
2024 NFL Game Log
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Snap Distribution / Depth Chart
Snap Counts
Snap %
San Francisco 49ers49ers 2024 RB Snap Distribution See more data like this | See last season's snap counts
I.Isaac Guerendo
#% of Team Snaps

11181%
43%
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Receiving Alignment Breakdown
See where Isaac Guerendo lined up on the field and how he performed at each spot.
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This Week's Opposing Pass Defense
How does the Vikings pass defense compare to other NFL teams this season?
The bars represents the team's percentile rank (based on QB Rating Against). The longer the bar, the better their pass defense is. The team and position group ratings only include players that are currently on the roster and not on injured reserve. The list of players in the table only includes defenders with at least 3 attempts against them.
MIN
@ Vikings
Sunday, Sep 15th at 1:00PM
Overall QB Rating Against
38.0
 
Cornerbacks
81.2
 
Safeties
7.8
 
Linebackers
26.0
 
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2024 Isaac Guerendo Split Stats
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Measurables Review View College Player Page
How do Isaac Guerendo's measurables compare to other running backs?
This section compares his draft workout metrics with players at the same position. The bar represents the player's percentile rank. For example, if the bar is halfway across, then the player falls into the 50th percentile for that metric and it would be considered average.
Height
6' 0"
 
Weight
221 lbs
 
40-Yard Dash
4.33 sec
 
Shuttle Time
4.15 sec
 
Cone Drill
6.94 sec
 
Vertical Jump
41.5 in
 
Broad Jump
129 in
 
Hand Length
9.25 in
 
Arm Length
30.75 in
 
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More Fantasy News
Set to suit up in season opener
RBSan Francisco 49ers
September 7, 2024
Guerendo (groin) practiced in full Saturday and doesn't have an injury designation for Monday's Week 1 contest against the Jets.
ANALYSIS
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Remains limited
RBSan Francisco 49ers
Groin
September 6, 2024
Guerendo (groin) remained limited in practice Friday, Nick Wagoner of ESPN.com reports.
ANALYSIS
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Opens week as limited participant
RBSan Francisco 49ers
Groin
September 5, 2024
Guerendo (groin) is practicing on a limited basis Thursday, Cam Inman of The San Jose Mercury News reports.
ANALYSIS
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Tweaks groin in practice
RBSan Francisco 49ers
Groin
August 28, 2024
Guerendo tweaked his groin Monday and won't practice this week, Cam Inman of The San Jose Mercury News reports.
ANALYSIS
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Healthy amount of action
RBSan Francisco 49ers
August 24, 2024
Guerendo (hamstring) rushed 11 times for 32 yards and caught both of his targets for three yards in Friday's preseason tilt against Las Vegas.
ANALYSIS
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Latest Fantasy Rumors
Behind CMC and Mitchell
RBSan Francisco 49ers
June 9, 2024
Guerendo is facing competition for the third spot on San Francisco's running back depth chart and is clearly behind both Christian McCaffrey and Elijah Mitchell, David Lombardi of The Athletic reports.
ANALYSIS
Lombardi mentions Guerendo's speed could come in handy as a return man on special teams, but as far as offense goes, the 2024 fourth-round draft pick out of Louisville doesn't appear to be headed for a prominent role as a rookie. Guerendo likely won't push McCaffrey or Mitchell for one of the top two spots on the depth chart, and he'll need to beat out incumbent third-stringer Jordan Mason and rookie undrafted free agent Cody Schrader for playing time.
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