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Tyjae Spears
Might be lead back against Indy
Spears could operate as the Titans' top running back for Sunday's AFC South clash against the Colts if Tony Pollard is unable to play due to an ankle injury, Jim Wyatt of the Titans' official site reports.
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Devin Singletary
Could reclaim RB1 duties Sunday
Singletary would serve as the Giants' top running back against the Falcons if rookie Tyrone Tracy is unable to play due to an ankle injury, Dan Salomone of the Giants' official site reports.
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Alexander Mattison
Could be Raiders' top back ROS
Mattison is in line to serve as Las Vegas' No. 1 running back for the final three games of the regular season due to Sincere McCormick being placed on injured reserve with an ankle injury.
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Sione Vaki
Lions' RB3 sans Montgomery
Vaki has been mostly limited to special teams work in his rookie season, but he has an opportunity to establish a larger role for himself in the backfield due to David Montgomery being sidelined with an MCL injury, Jared Ramsey of the Detroit Free Press reports.
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Kenneth Walker
All clear for big Week 16 game
Walker, who's missed the last two games due to calf and ankle injuries, does not have a designation for Sunday's game against the Vikings, Brady Henderson of ESPN.com reports.
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Alvin Kamara
May be done for season
A source told ESPN's Adam Schefter that Kamara's adductor injury may be season-ending, Katherine Terrell of ESPN.com reports.
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Kendre Miller
Likely lead back Monday
Miller's in line to lead the Saints backfield Monday against the Packers, as coach Darren Rizzi said Thursday that Alvin Kamara isn't likely to play Monday at Green Bay, Nick Underhill of NewOrleans.Football reports.
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Patrick Taylor
Next man up with Guerendo hurt
Taylor will likely take on a lead role in Week 16, as Isaac Guerendo is expected to miss Sunday's game against the Dolphins due to a hamstring injury, Adam Schefter of ESPN reports.
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Isaac Guerendo
Expected to miss Week 16
Guerendo is expected to miss Sunday's game against the Dolphins due to a hamstring injury, Adam Schefter of ESPN reports.
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Clyde Edwards-Helaire
Lands with Saints
Edwards-Helaire, who was waived by the Chiefs on Monday, signed with the Saints' practice squad Wednesday, Katherine Terrell of ESPN.com reports.
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Joe Mixon
Confident after injury scare
Mixon is confident in his ability to deliver a strong performance in Week 16 against Kansas City despite suffering a minor ankle injury in Sunday's win over the Dolphins, Aaron Wilson of KPRC 2 Houston reports.
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Jonathan Taylor
Premature celebration proves costly
Taylor dropped the ball before crossing the goal line as he celebrated prematurely on what should have been a 41-yard touchdown but instead turned into a touchback in Sunday's 31-13 loss to the Broncos, per James Boyd of The Athletic.
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Jerome Ford
Back in lead role with Chubb hurt
Ford is expected to work as Cleveland's top running back for the remainder of the season, as coach Kevin Stefanski relayed that Nick Chubb broke his foot during Sunday's 21-7 loss to the Chiefs, per Daniel Oyefusi of ESPN.com.
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Braelon Allen
Dip in workload likely Sunday
Allen is expected to see a decrease in his workload during Sunday's Week 15 game against the Jaguars as a result of Breece Hall being expected to play through his questionable tag, per Adam Schefter of ESPN.
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Breece Hall
Officially expected to play Sunday
Hall, who's listed as questionable due to a knee injury for Sunday's Week 15 matchup against the Jaguars, is expected to play, Adam Schefter of ESPN reports.
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Breece Hall
Week 15 outlook improves
Interim Jets coach Jeff Ulbrich expressed optimism Friday regarding Hall's availability for Sunday's game against the Jaguars, per Rich Cimini of ESPN.com. "He looks good right now, so it's promising," Ulbrich said of Hall, who is listed as questionable after practicing without limitations Friday.
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Tony Pollard
Likely to suit up Week 15
Pollard is expected to play through his ankle injury Sunday against the Bengals, per Terry McCormick of TitanInsider.com.
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Zach Charbonnet
Appears headed for another start
Charbonnet appears set to draw a second straight start Sunday night against the Packers due to Kenneth Walker being listed as doubtful due to his calf injury, Brady Henderson of ESPN.com reports.
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Kenneth Walker
Expected to miss Week 15
Walker, who's dealing with a calf injury, is listed as doubtful for Sunday night's game against the Packers, Brady Henderson of ESPN.com reports.
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Braelon Allen
Likely to split with Davis again
Allen's likely to maintain a prominent role in Week 15 against the Jaguars, as coach Jeff Ulbrich said Wednesday that Breece Hall is "struggling a bit" with the knee injury that sidelined the starting running back in Week 14 against Miami, per Rich Cimini of ESPN.com.
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Isaiah Davis
Likely to retain elevated role
Davis is in line for a prominent role in Week 15 against the Jaguars, as coach Jeff Ulbrich said Wednesday that Breece Hall is "struggling a bit" with the knee injury that sidelined the starting running back in Week 14 against Miami, per Rich Cimini of ESPN.com.
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Breece Hall
Pessimism over Week 15 availability
Coach Jeff Ulbrich said Wednesday that Hall is "struggling a bit" with a knee injury, per Rich Cimini of ESPN.com, so Hall looks unlikely to return in Week 15 against the Jaguars.
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Patrick Taylor
Likely to remain backup Week 15
Taylor's expected to remain in a backup role Thursday against the Rams, as sources tell Adam Schefter of ESPN that Isaac Guerendo plans to play despite spraining his foot in Sunday's win over the Bears.
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Isaac Guerendo
Plans to play Thursday
Sources tell Adam Schefter of ESPN that Guerendo plans to play Thursday night against the Rams despite spraining his foot in Sunday's win over the Bears.
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Breece Hall
No sign season is over
The Jets haven't indicated they view Hall's knee injury as something that would require shutting him down for the rest of the season, Adam Schefter of ESPN reports.
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